ABSTRACT
Background: The incidence of ocular injuries in India is estimated to be 20.5% affecting mainly those aged less than 40 years and males. Cataract is the commonest complication after ocular injury resulting from either penetrating injuries from sharp objects like stick or thorn or with blunt trauma by objects like stone, cricket ball etc. The present study aims to find out the visual outcome of traumatic cataract cases. Material and methods: This was a cross sectional study conducted among 40 traumatic cataract cases attending outpatient units of SVRR Government General Hospital, Tirupati during July 2014 to June 2015. A predesigned interview schedule was used to collect the necessary information. All patients had undergone Posterior Chamber Intra Ocular Lens Implantation and visual outcome was assessed after 15 days, 6 weeks, 3 months and 6 months. The results were analyzed using MS excel software and Epiinfo 7 version statistical software. Results: It was found that a large majority of the cases were aged less than 40 years (67.5%) and males (62.5%). The most common type of cataract developed was found to be ‘white soft’ type (47.5%). In 52.5% of patients, the time lag between injury and surgery was found to be 1 week to 1 month. It was found that 70% patients had regained vision (>6/18) after surgery. Conclusion: Posterior Capsular Intra Ocular Lens Implantation is highly effective in restoring vision in traumatic cataract cases. The time lag between injury and surgery should be as short as possible for complete recovery. There should be quick referral of traumatic cataract cases to the specialized ophthalmic care units depending on condition of patients.
ABSTRACT
Background: Cardiovascular disease, resulting from atherosclerosis, is a leading cause of global morbidity and mortality. Classical risk factors explain much of the attributable risk for cardiovascular events, but other risk factors for the development and progression of atherosclerosis, which can be identified, may be important therapeutic targets. Infectious agents, such as Chlamydia pneumoniae, have been proposed as contributory factors in the pathogenesis of atherosclerosis. The present study was conducted to determine the seroprevalence of C. pneumoniae antibodies and to study the association of chronic C. pneumoniae infection with Coronary Artery Disease (CAD). Methods: The study group included 90 angiographically proven CAD patients and age and sex matched 90 normal coronaries as control group. With total aseptic precaution 3 ml blood was collected. Enzyme linked immunosorbant assay was performed for all subjects to detect the presence of IgG and IgA antibodies to Chlamydia pneumoniae (Cp). Results: IgG and IgA Cp antibodies were detected in 67.8% and 58.9% CAD patients compared to 45.6% and 11.1% controls. IgG + IgA Cp antibodies were detected in 88.9% CAD patients when compared to 50.0% controls. Seroprevalence of IgG and IgA Cp antibodies were high among CAD patients compared to controls and was found statistically significant. A significant presence of Chlamydia pneumoniae antibodies was detected in smokers, diabetes mellitus, hypertension, and dyslipidemia. Conclusion: In the present study, the seroprevalence of IgG and IgA Cp antibodies was found to be higher in CAD patients compared to controls. The present study supports the association between Chlamydia pneumoniae infection and Coronary artery disease.
ABSTRACT
To test the hypothesis that palatal bone is able to support miniscrews when subjected to forces generatedduring orthodontic treatment. Finite element method software ANSYS10.0 was used. Tests were done in a state of osseointegration and non osseointegration. Two different palatal regions i.e. one layer of cortical bone and underlying trabecular bone; & two layers of cortical bone with trabecular bone in between were involved. In both cases, for each configuration, two different forces of 240 gfand480 gf were applied to the screws. These load values corresponded to those generated by the application of an orthodontic appliance to the miniscrew. The results showed that miniscrew inserted into the palate can be anchored to bone and loaded within orthodontic force range without bone fracture. The osseointegrated system was characterized by lower level of stress than non osseointegrated but anchorage within the second layer of cortical bone reduced the stress on the trabecular bone, improving stability of the implant. We conclude that miniscrews loaded within the normal orthodontic force range do not exceed stress levels that lead to bone fracture.